Profits First, Health Second: The Pharmaceutical Industry and the Global South; Comment on “More Pain, More Gain! The Delivery of COVID-19 Vaccines and the Pharmaceutical Industry’s Role in Widening the Access Gap”

Document Type : Commentary

Author

1 School of Health Policy and Management, York University, Toronto, ON, Canada

2 Department of Family and Community Medicine, University of Toronto, Toronto, ON, Canada

Abstract

The pharmaceutical industry has a long history of prioritizing the research and sale of medicines that will yield the largest amount of revenue and placing the health of people second. This gap is especially prevalent in countries of the Global South. This article first explores the dichotomy in research between the Global North and the Global South and then looks at examples of how access to key medicines used in diseases such as HIV, oncology and hepatitis C is limited in the latter group of countries. The role of pharmaceutical companies during the COVID-19 pandemic prompted negotiations for a pandemic accord that would ensure more equity in both research and access when the next pandemic comes. However, efforts by a combination of the pharmaceutical industry and some high-income countries (HICs) are creating serious obstacles to achieving the goal of an accord that would place health over profits.

Keywords

References

  1. Borges L, de Menezes H, Crosbie E. More pain, more gain! The delivery of COVID-19 vaccines and the pharmaceutical industry’s role in widening the access gap. International Journal of Health Policy and Management. 2022;11(12):3101-3113. doi:10.34172/ijhpm.2022.6942
  2. G-Finder: neglected disease research and development: the status quo won’t get us there. 2022; https://policy-cures-website-assets.s3.ap-southeast-2.amazonaws.com/wp-content/uploads/2023/02/09104948/2022-G-FINDER-Neglected-Disease-report.pdf. Accessed February 17, 2024.
  3. May E, Taylor K, Gupta L, Miranda W. Seize the digital momentum: measuring the return from pharmaceutical innovation 2022. 2023; https://www2.deloitte.com/content/dam/Deloitte/uk/Documents/life-sciences-health-care/deloitte-uk-seize-digital-momentum-rd-roi-2022.pdf. Accessed February 17, 2024.
  4. Senior M, Hadjivasiliou A. Orphan drugs 2023-2028: a flattening curve? 2023; https://www.evaluate.com/orphan-drug-2023-report. Accessed February 17, 2024.
  5. Pedrique B, Strub-Wourgaft N, Some C, et al. The drug and vaccine landscape for neglected diseases (2000–11): a systematic assessment. Lancet Global Health. 2013;1:e371-e379. doi:http://dx.doi.org/10.1016/S2214-109X(13)70078-0
  6. Kong A, Warren M, Edwards D, Karrar K, Iyer J. Are pharmaceutical companies making progress when it comes to global health? Amsterdam May 2019.
  7. Homedes N, Ugalde A. Availability and affordability of new medicines in Latin American countries where pivotal clinical trials were conducted. Bulletin of the World Health Organization. 2015;93(10):674-683. doi:http://dx.doi.org/10.2471/BLT.14.151290
  8. Miller J, Mello M, Wallach J, et al. Evaluation of drug trials in high-, middle-, and low-income countries and local commercial availability of new approved drugs. JAMA Network Open. 2021;4(5):e217075. doi:10.1001/jamanetworkopen.2021.7075
  9. Herder M, Graham J, Gold R. From discovery to delivery: public sector development of the rVSV-ZEBOV Ebola vaccine. Journal of Law and the Biosciences. 2020;7(1):lsz019. doi:10.1093/jlb/lsz019
  10. Jack A. Novartis chief in warning on cheap drugs. Financial Times. September 30, 2006.
  11. Transcript of Bayer CEO Marjin Dekkers quote at the December 3, 2013 FT Event, regarding India compulsory license of Nexavar. 2014; https://www.keionline.org/22414. Accessed February 17, 2024.
  12. Ford N, Wilson D, Chaves G, Lotrowska M, Kijtiwatchakul K. Sustaining access to antiretroviral therapy in developing countries: lessons from Brazil and Thailand. AIDS. 2997;21:S21-S29. doi:10.1097/01.aids.0000279703.78685.a6
  13. Frontline AIDS. How patents affect access to HIV treatment. 2019; https://frontlineaids.org/how-patents-affect-access-to-hiv-treatment/. Accessed April 14, 2024.
  14. Gabble R, Kohler J. “To patent or not to patent? the case of Novartis’ cancer drug Glivec in India.” Globalization and Health. 2014;10:3. doi:10.1186/1744-8603-10-3
  15. Rockers P, Wirtz V, Umeh C, Swamy P, Laing R. Industry-led access-to-medicines initiatives in low- and middle-income countries: strategies and evidence. Health Affairs. 2017;36(4):706-713. doi:10.1377/hlthaff.2016.1213
  16. Moon S, Jambert E, Childs M, von Schoen-Angerer T. A win-win solution?: A critical analysis of tiered pricing to improve access to medicines in developing countries. Globalization and Health. 2011;7:39. doi:https://doi.org/10.1186/1744-8603-7-39
  17. Anderson S. Pharmaceutical CEOs to G7: protect intellectual property rights and pathogen access in WHO pandemic accord. 2023; https://healthpolicy-watch.news/pharmaceutical-ceos-to-g7-protect-intellectual-property-rights-and-pathogen-access-in-who-pandemic-accord/#:~:text=CEOs%20from%20the%20world%27s%20largest,Organization%27s%20(WHO)%20pandemic%20treaty. Accessed February 17, 2024.
  18. Research funders must join the fight for equal access to medicines. Nature. 2024;626(7997):7-8. doi:10.1038/d41586-024-00237-y

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History

  • Receive Date: 20 February 2024
  • Revise Date: 14 April 2024
  • Accept Date: 17 April 2024
  • First Publish Date: 20 April 2024

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